Such tests are increasingly moving beyond their origins in cutting-edge research and into the laboratory and diagnostic ...

The study’s researchers scanned the brains of older women who have used HT, observing tau accumulation, a hallmark of Alzheimer disease.

An international team of researchers, led by Massachusetts General Hospital and Harvard Medical School, has conducted a ...

结果发现 Aβ 先于 tau 沉积且影响网络。该研究助力理解 AD 机制，为早期诊断和干预提供方向，值得科研人员一读。 在阿尔茨海默病（Alzheimer's disease，AD）的研究领域，一直存在着诸多谜团等待科学家们去解开。淀粉样蛋白 β（Amyloid-beta，Aβ）和 tau 蛋白的沉积 ...

Gene Hackman’s wife died of hantavirus, but could his own death be linked to infection? New research suggests infections may ...

Alzheimer’s is sometimes caused when certain proteins, called β-amyloid (Aβ) and tau, build up in the brain, leading to ...

*仅供医学专业人士阅读参考合适的血液检测标志物，无疑是应对各种疑难杂症的致胜法宝之一。对于阿尔茨海默病（AD）这种神经退行性疾病，早期诊断对于疾病管理和干预至关重要。尽管脑脊液（CSF）和影像学检查已经被证明在AD诊断中具有高准确性，但它们都存在一定的局限性，例如侵入性强、成本较高、时间消耗大等。相比之下， ...

Herpesvirus infection may contribute to Alzheimer’s disease through transposable element activation and neuroinflammation.

失智症正以每3秒新增1例患者的速度威胁人类认知健康。目前全球约5500万失智症患者，其中60%～70%是由 阿尔茨海默病（Alzheimer's Disease, AD） 导致的。这一数字预计将在2050年突破1.52亿——相当于俄罗斯现有人口的规模 ...

A new study by Mass General Brigham researchers has found faster accumulation of tau—a key indicator of Alzheimer's ...

为探究免疫信号对阿尔茨海默病（AD）影响，研究人员靶向 Il10 和 Il4 信号，发现诱饵受体可减轻 Aβ 积累，提供新治疗思路。 研究人员在研究中用到了多种关键技术方法。首先，他们使用了腺相关病毒（AAV）技术，将编码可溶性 Il10 受体（sIl10R）和可溶性 Il4 受体（sIl4R）的基因导入小鼠大脑。其次，运用 RNA ...