This study highlights the importance of proteins that are involved in the regulation of the actin cytoskeleton, revealing fundamental roles for HEM1 in both innate and adaptive immune cells.

The cytoskeleton ... in protein composition. Microtubules are the largest type of filament, with a diameter of about 25 nanometers (nm), and they are composed of a protein called tubulin. Actin ...

In all eukaryotic cells, actin protein assembles to form a network of thin filaments that spread throughout the cell. The actin filaments give the cell its structure, enable the cell to move, and ...

We recently discovered that these structures are essential for the establishment of reticular adhesions. In our lab, we aim to elucidate the interplay of clathrin structures with the actin ...