The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

There may be a conserved architecture of condensed chromatin, for example ... of four nucleosomes at 9-Å resolution showed two pairs of nucleosomes interacting through their flat faces, with ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Single-cell multiomic analyses reveal known and new genes and pathways involved in the development of germ cells and provide a discovery platform for the scientific community.

More information: Irina V Zhegalova et al, Convergent pairs of highly transcribed genes restrict chromatin looping in Dictyostelium discoideum, Nucleic Acids Research (2025). DOI: 10.1093/nar/gkaf006 ...

The accessible chromatin regions of GhCKI promoter in upland ... The deletion (−) base pairs are indicated by numbers. EP, epidermis; EN, endothecium; ML, middle layer; T, tapetum; MAM ...