and mutations in either of these genes leads to ineffective mismatch repair, failure to induce apoptosis, and cancer. Because mutations in hMSH2 or hMSH6 result in resistance to mutagens and DNA ...

However, the mechanistic connections between mismatch DNA repair and selective neuronal vulnerability in Huntington's disease remained unknown. The new study from UCLA Health and Jane and Terry ...

DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

Diets low in carbohydrates and soluble fibres can drive the growth of polyps in the colon, increasing the risk of developing ...

However, the mechanistic connections between mismatch DNA repair and selective neuronal vulnerability in Huntington's disease remained unknown. The new study from UCLA Health and Jane and Terry ...

Researchers from the University of Toronto have shown how a low-carbohydrate diet can worsen the DNA-damaging effects of some ...

These strains had genetic changes in genes that control the fungus's system which repairs mutated DNA—known as the mismatch repair system. By using CRISPR-Cas9 to reproduce these variants in the ...

University of Toronto researchers have shown how a low carbohydrate diet can worsen the DNA-damaging effects of some gut ...

Researchers have shown how a low carbohydrate diet can worsen the DNA-damaging effects of some gut microbes to cause colorectal cancer. The study compared the effects of three different diets in ...