The RNA exosome complex is a crucial component of cellular machinery responsible for the degradation and processing of RNA molecules. This multi-subunit ribonuclease complex plays a vital role in ...
After decapping, 5’ to 3’ RNA degradation is accomplished by Xrn1, a 5’ to 3’ exoribonuclease. In the 3’ to 5’ pathway, RNA degradation is catalyzed by a multi-subunit 3’ to 5’ exoribonuclease complex ...
The eukaryotic RNA exosome is a 9–11-subunit 3′→5′ exoribonuclease complex that catalyses cellular RNA degradation. Liu et al. determined the structure of the reconstituted 9-subunit 286 ...
Building on the discovery and characterisation of the exosome ribonuclease complex (Mitchell et al., 1997; Allmang et al., 1999), my lab’s research addresses the molecular mechanisms of RNA quality ...
The ability of exosomes to facilitate targeted delivery and modulate immune responses enhances their appeal in treating complex diseases. Additionally, advancements in isolation and ...
However PureTech says its milk-derived exosomes have evolved naturally to transport complex biological molecules. PureTech Health will receive up to $36 million, including upfront payments ...
Behfar. "This year, we are thrilled to share how our innovative platform is advancing solutions for complex medical challenges and bringing hope to patients worldwide." Since its inception in 2017, ...