Santucci and colleagues investigated the role of tumor necrosis factor receptor superfamily member 18 (Tnfrsf18, formerly Gitr) in two mouse models of colitis. Tnfrsf18 is highly expressed on ...

Glucocorticoid-induced tumor necrosis factor receptor (GITR) and its ligand, GITRL, are involved in immune response regulation. GITR is mainly expressed in activated T cells while GITRL is primarily ...