Activation of hepatic stellate cells is the central event in hepatic fibrosis. These perisinusoidal cells orchestrate an array of changes including degradation of the normal ECM of liver ...

Cellular senescence, where cells permanently stop dividing, plays a complex role in liver health. In a recent review article, ...

The rate of progression of fibrosis in an individual patient with chronic liver disease cannot be predicted ... Efforts are under way to exploit the human genome sequencing in order to identify ...

Inflammation and cell death are key triggers of hepatic fibrogenesis in NAFLD, with hepatic stellate cells (HSCs) playing a ...