In addition, nuclear expression of Lamin B1 progressively declined in Iba1-positive cells during advance paralysis. Figure 2C shows subpopulation of Iba1-positive microglia that devoid of nuclear ...

and their ratio to total Iba1+ number was calculated. The ratio was then divided by the imaged area, and the mean for each group was calculated. Altogether, our data show lower microglial cell density ...

Microglia and presynaptic changes were indexed using Iba1 and SV2A immunostaining. Pearson correlation and t-tests were used (significance p<0.05). Results We found a significant reduction in synaptic ...