We also need to identify the proteins that interact with these sequences to initiate and/or regulate the recombination process; PRDM9 is the only such protein to be identified, but there are ...

The authors generated mutant mice in which the RAG proteins could interact with and bind to DNA normally without initiating V(D)J recombination and assessed RAG protein binding, as well as the ...

Scientists at deCODE genetics/Amgen have constructed a complete map of how human DNA is mixed as it is passed down during ...

These include the ATM and NBS1 proteins that are part of the DSB sensing complex, and the BRCA2 protein that binds to the resected ssDNA (Yang et al., 2002) and catalyzes the formation of the ...

Our long-term goals are to exploit the molecular genetic systems we have developed to understand the role of homologous recombination in maintaining genetic stability. We are determining factors that ...

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.

Recombinant yeast cells can be used as a vector to produce proteins that would normally be found in animals or plants. Recombinant yeast cells are used during DNA Recombinant technology as they ...

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that ...

Researchers from UW Medicine and the Technical University of Denmark have developed computationally designed proteins to ...

The market research report covers analysis of key stakeholders in the global therapeutic protein market. Some of the leading players profiled in the report include: AbbVie Inc. Alexion Pharmaceuticals ...