It is well established that, in many instances, ligand binding to a receptor triggers the internalization ... By contrast, the bulk of endocytosis is often viewed as a constitutive process that ...

Inhibition of AMPA receptor endocytosis could help treat addiction to heroin. Van den Oever et al. have used a rat model to demonstrate that the link between re-exposure to preconditioned stimuli ...

One key process in maintaining this equilibrium is endocytosis, the mechanism by which membrane components are internalised. Organisms have evolved various endocytic pathways, all relying on ...

it sometimes requires an additional factor such as a protein that is a receptor for a specific chemical serving as a "named ticket to entry" into the cell. One can call its endocytosis that is a ...

Revive Therapeutics (RVVTF) announced an update on the research study evaluating Bucillamine as a potential treatment for nerve agent exposure, ...

The DRDC have the first set of animals (soman controls and bucillamine pretreated) completed and is now performing the assays looking at GABA receptor downregulation. Over the next few weeks data will ...

Reduced receptor-mediated LDL endocytosis causing raised blood LDL cholesterol (LDL-C) is the main defect, but other abnormalities due to lack of LDL receptors include altered hepatic cholesterol ...