BMJ1d
Association between midlife dementia risk factors and longitudinal brain atrophy: the PREVENT-Dementia study
Background Increased rates of brain atrophy on serial MRI are frequently used as a surrogate marker of disease progression in Alzheimer’s disease and other dementias. However, the extent to which they ...
BMJ1d
Combining 7T T2 and 3T FGATIR: from physiological to anatomical identification of the subthalamic nucleus borders
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BMJ6d
Brain tumours: incidence, survival, and aetiology
Correspondence to: Dr Patricia A McKinney Paediatric Epidemiology Group, Unit of Epidemiology and Health Services Research, University of Leeds, 32 Hyde Terrace, Leeds LS2 9LN, UK; ...
BMJ3d
Central nervous system neuronal surface antibody associated syndromes: review and guidelines for recognition
The concept of antibody mediated CNS disorders is relatively recent. The classical CNS paraneoplastic neurological syndromes are thought to be T cell mediated, and the onconeural antibodies merely ...
BMJ11d
Effect of a multidisciplinary amyotrophic lateral sclerosis (ALS) clinic on ALS survival: a population based study, 1996–2000
Background: In recent years, there has been a paradigm shift in the method of healthcare delivery to amyotrophic lateral sclerosis (ALS) patients with the emergence of multidisciplinary ALS clinics ...
BMJ10d
Predicting disability progression and cognitive worsening in multiple sclerosis using patterns of grey matter volumes
Correspondence to Elisa Colato, Russell Square House, 10-12 Russell Square, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, ...
BMJ7d
Anterior spinal hernia: an increasingly recognised cause of thoracic cord dysfunction.
Two cases of anterior spinal hernia are presented. The medical literature is reviewed, the syndrome characterised, and its cause and treatment discussed. The patient is typically middle aged with a ...
BMJ11d
Intracerebral implantation of human neural stem cells and motor recovery after stroke: multicentre prospective single-arm study (PISCES-2)
Background Human neural stem cell implantation may offer improved recovery from stroke. We investigated the feasibility of intracerebral implantation of the allogeneic human neural stem cell line ...
BMJ10d
Patient with ALS with a novel TBK1 mutation, widespread brain involvement, behaviour changes and metabolic dysfunction
Correspondence to Dr Frederik J Steyn, Centre for Clinical Research, The University of Queensland, Brisbane, QLD 4072, Australia; f.steyn{at}uq.edu.au This male patient was first seen at age 62 years ...
BMJ5d
Myelin oligodendrocyte glycoprotein-associated disorders are associated with HLA subtypes in a Chinese paediatric-onset cohort
Objective Myelin oligodendrocyte glycoprotein-associated disorders (MOGADs) are a rare new neurological autoimmune disease with unclear pathogenesis. Since a linkage of the disease to the human ...
BMJ5d
Progressive myoclonic epilepsy as an adult-onset manifestation of Leigh syndrome due to m.14487T>C
Background: m.14487T>C, a missense mutation (p.M63V) affecting the ND6 subunit of complex I of the mitochondrial respiratory chain, has been reported in isolated childhood cases with Leigh syndrome ...
BMJ14d
Neurofilament light chain in serum for the diagnosis of amyotrophic lateral sclerosis
5 Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Correspondence to Professor Markus Otto, Department of Neurology, University of Ulm, Ulm 89081, Germany; ...