Crucially, key literature relevant to this research, addressing the role of ICAM1 endocytosis in antigen-presenting cells, has not been taken into consideration. The manuscript by Xu et al. studies ...

Hepatocellular carcinoma (HCC), the third leading cause of cancer-related deaths worldwide, remains one of the most ...

Researchers from the VIB-KU Leuven Center for Cancer Biology, in collaboration with other scientists, have discovered a way ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

There were 236 differentially expressed genes (DEGs) between health and active CD in the CD8+ T cells, and 451 DEGs in the γδ+ T cells. Common pathways upregulated in coeliac disease included those ...

Additionally, local inflammation initiates the production of chemokines and the recruitment of immune cells, including CD8 + T cells. However, how the recruited immune cells and the chemokine system ...

Recently, ICB efficiency has been linked to reinvigoration of T cells with a non-terminally dysfunctional phenotype. Here, we investigate the effect of FOLFOX on CD8 T cell tumor accumulation, ...

1School of Basic Medical Science, Southern Medical University, Guangzhou, China. 2Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China. 3Zenith Institute of ...

*仅供医学专业人士阅读参考各种各样的代谢和营养物质，往往能左右免疫细胞和癌细胞争战的胜负，从代谢角度入手干预来增敏免疫治疗，也是奇点糕常常会聊到的热门课题。但是吧，代谢和营养物质向抗肿瘤免疫应答施加的影响并不都是相同的，到底是“有你很重要”，还是“没 ...