Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer ...

Chromatin is a flexibly joined chain of nucleosomes that exists inside the nucleus of eukaryotic cells and has been ... genes into a dynamic and accessible structure. The study challenges the ...

This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These ...

GET, a novel computational model, accurately predicts gene activity by analyzing chromatin accessibility and DNA sequences ...

1Department of Immunology, Center for Systems Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. 2School of Medicine, Tsinghua University, Beijing, China.

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

What is multi-omics? Multi-omics is the integration of multiple omic data during analysis. Omic data principally includes ...

Researchers have identified a unique stem cell in the young brain capable of maturing into multiple cell types, potentially explaining the origins of autism and glioblastoma.

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.