Beyond the ladder-like structure described above, another key characteristic of double-stranded DNA is its unique three-dimensional shape. The first photographic evidence of this shape was ...
DNA is negatively charged ... Thus, the 30-nanometer fiber may be highly irregular and not quite the uniform structure depicted in instructive drawings such as Figure 1 (Bednar et al., ...
Earlier that morning, in the nearby Cavendish laboratory, the two scientists had discovered the structure of deoxyribonucleic acid, or DNA. This discovery changed the world of science and medicine ...
With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This ...
This way DNA can reproduce itself without changing its structure -- except for occasional errors, or mutations. The structure so perfectly fit the experimental data that it was almost immediately ...
But James Watson and Francis Crick's claim was a valid one, for they had in fact discovered the structure of DNA, the chemical that encodes instructions for building and replicating almost all ...
MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a ...
New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop ...
By unveiling Pol-theta's DNA-bound structure—its active state—the study provides a blueprint for designing more effective ...
Kossel isolated cytosine from calf thymus tissues and found that it was a component of nucleic acids. This discovery, along with the identification of other nitrogenous bases, laid the foundation for ...
In the new work, Rothemund and his colleagues used DNA origami to create a lilypad-like structure—a flat, circular surface about 100 nanometers in diameter, tethered by a DNA linker to a gold ...
Each ODN in the Takumi-shaped DNA structure was constructed with an eight-18 nucleotide-long palindromic stem attached to two cohesive parts on either side with a thymidine (T) spacer.