Diabetic nephropathy remains a major complication ... It examines the impact of mTOR on podocytes, glomerular mesangial cells, renal tubular epithelial cells, and glomerular endothelial cells ...

Polycystic kidney disease (PKD), a family of genetic disorders that causes clusters of cysts to form on the kidney, is among the most common genetic disorders, affecting some 500,000 people in the ...

Glomerular cell biology is a core strength of the Bristol Renal group. We have an international reputation ... These conditions include diabetic nephropathy, membranous nephropathy and FSGS. We ...

Renal tubule epithelial cells can be oval to columnar in shape, depending on the segment of the tubule they come from. They are considered to be a marker of tubular damage. When seen with granular ...

Intravenous single-dose studies in normal subjects demonstrate that metformin is excreted unchanged in the urine by renal tubular secretion. The addition of cimetidine 400 mg to metformin 250 mg ...

Circulating kidney injury molecule-1 (KIM-1) predicts survival outcomes in patients with metastatic renal ... in clear cell and papillary RCC, but it is also expressed in proximal tubular kidney ...