In this study, we investigated the mechanisms by which high mobility group box protein 1 (HMGB1) acts to accelerate muscle fatigue development. Results Our results demonstrate that TLR4 is expressed ...

Toll-like Receptor 4 (TLR4): A protein that plays a key role in the immune system by recognizing pathogens and activating inflammatory responses. High Mobility Group Box 1 (HMGB1): A protein that ...

Research has demonstrated that many natural products exert notable anti-inflammatory effects by modulating the Toll-like receptor 4 (TLR4) and nuclear factor kappa B (NF-κB) signaling pathways. The ...

Recent studies reported an interplay between the receptor for advanced glycation end products (RAGE) and its ligands, S100 protein group, advanced glycation end products (AGEs) and high-mobility group ...

Immunotherapy. 2012;4(3):323-334.

The twin-lens camera design looks like an exercise in optical redundancy, a mechanical kludge superseded by later and better viewing technologies. That’s what a TLR looks like. But in designing a ...

Oxidative Stress: Neuropathy, Excitability, and Neurodegeneration.

From the Centers of Inflammation, Translational, and Clinical Lung Research (Y. Shao, Y. Sun, Y.L., F.S., C.D., C.J., K.X., X.J., X.Y.), Temple University, Lewis Katz ...

Department of General Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China Hubei Key Laboratory of Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan, Hubei ...