研究结论和讨论部分指出，该研究揭示了 KDM3A 在出生后海马神经发生中的关键作用，它通过转录和翻译后调控 Wnt/β -catenin 信号通路，影响 NSPCs 的增殖和分化。这不仅加深了我们对海马神经发生复杂调控机制的理解，也为治疗神经系统疾病和促进脑损伤修复提供了新的潜在靶点和治疗策略。此外，Quercetin 作为一种能够调节 KDM3A ...

Finally, the 1.28-ppm signal intensified in the adult rodent hippocampus following electroconvulsive shock (ECS), a treatment that is known to increase neurogenesis in this area. Together ...

In the latest study, Shawn Sorrells and Mercedes Paredes of the University of California, San Francisco, and their colleagues wanted to search for evidence of neurogenesis in human brains and test a ...

“We provide thorough information on the extent of neurogenesis and we show that there is surprisingly large amount,” said study author Jonas Frisén of the Karolinksa Institute in Stockholm, Sweden.

More information: Guy Shapira et al, ADNP is essential for sex-dependent hippocampal neurogenesis, through male unfolded protein response and female mitochondrial gene regulation, Molecular ...

Adult neurogenesis takes place in the hippocampus, a brain region controlling aspects of cognition and emotional behavior.

Larger hippocampal volume could be due to neurogenesis, the formation of new neurons, or a virus in the brain. Professor Marshall-Gradisnik said, "The NCNED brings together a critical mass of ...

Mitochondrial fusion grants new neurons a competitive advantage Adult neurogenesis takes place in the hippocampus, a brain region controlling aspects of cognition and emotional behavior.

Within the irradiated hippocampus, precursor proliferation is reduced by 62% and neuro-genesis is almost entirely ablated. The absence of neurogenesis could be due to the dysfunction and/or loss ...