The neural crest is an essential part of the embryo, and this region of cells forms the bones of our face and neck, as well as parts of the nervous system. Dr. Barriga and colleagues found that ...

Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study led by UCL researchers.

To investigate this possibility in a controlled experimental situation, cranial neural crest explant cultures were exposed to different concentrations of ISO (2 and 20 ug/ml medium) and cell ...

This gave rise to epidermal cells, and cranial neural crest cells, which gave rise to cells of the dermis in the face. After the cells grew for 70 days as spherical aggregates, the first hair ...

This recently published exploration into the subventricular zone (SVZ) highlights its critical role in neural regeneration, ...

Right panels: Lab-grown cortical interneurons from human pluripotent stem cells are tools to study psychiatric disorders. Specific functional, electric firing properties of those neurons are shown by ...

Other iPSC-based models affecting neural crest lineages include Schwann cell and melanocyte-related disorders, including our effort to model human melanoma in pluripotent stem cells. Modeling herpes ...

In my lab, we are interested in understanding the developmental evolution of our own subphylum, the vertebrates. To do this, we study developmental gene expression, regulation, and function in three ...