Over the last decade, organoids have become an increasingly popular platform for modeling organ function and disease. 3 However, the generation of fetal organoids is complicated by ethical and legal ...

The bank has since established more than 2,300 cancer cell lines and organoids — 3D clusters of cultured cells that mimic the complex behaviour of living organs — using tissue samples from ...

Sironax' lead RIPK1 drug, SIR0365, has completed two phase 1b studies including one looking at its potential as a treatment for severe hyperinflammation associated with COVID-19 infections, while ...

Organoids are 3D cell culture models that more accurately reflect the structural and functional complexities of organs in vitro than traditional 2D cell culture methods. Generally derived from stem ...

Institute of Cancer Research UK has identified proteolysis targeting chimeras (PROTACs) comprising a Von Hippel-Lindau disease tumor suppressor (VHL) binding moiety coupled to a receptor-interacting ...