RNAs are an incredibly valuable but severely underexploited class of drug ... in RNA-targeted small-molecule drug design and development. Azor has developed AI and physics-based computational ...

“Among other benefits, RNA-based drugs overcome a key problem: patient adherence to medications for chronic conditions,” says Ray. “Instead of relying on the patient to take more than 300 ...

Researchers at Tel Aviv University have achieved a breakthrough in drug delivery: they have successfully transported lipid nanoparticles encapsulating messenger RNA (mRNA) to the immune system of ...

Biogen has made a further push into RNA-based drug discovery via a collaboration with Envisagenics, which applies artificial intelligence RNA sequencing data to discover new drug targets and ...

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive ...

A new study published in the journal eLife on February 4, 2025, may lead to breakthroughs in RNA-based drug development. University of Maryland researchers used microscopic roundworms as a model ...

Vice President RNA Formulation & Drug Delivery, BioNTech RNA Pharmaceuticals Development of Formulations for Delivery of RNA and Small Molecules Shalini Andersson, Senior Director and Head of New ...

RNA-based drug discovery for spinal muscular atrophy: a story of small molecules and antisense oligonucleotides.

“But this is just a proof-of-concept study. By tweaking the nanoparticle composition, we could deliver other RNA-based drugs to different organs. There’s a saying: “’’It’s all in the ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA vaccines and double-stranded RNA (dsRNA) therapies. But while health care ...

The failures of ophthalmology drug development ... company's RNA-based therapy for Dravet syndrome is not just another seizure treatment but a potential breakthrough in disease modification ...