Purpose: The mechanism of action and pharmacokinetics of sirolimus when used as part of a drug-eluting stent (DES) and the efficacy and cost of using DESs versus bare-metal stents are discussed.

Aging significantly impacts neurodegeneration, increasing risks for diseases like Alzheimer's. Research focuses on therapies to enhance cognitive function.

The detailed mechanisms by which inflammatory cells and cytokines promote intestinal ... Granulocyte-Macrophage Colony-Stimulating Factor; IL-4, Interleukin-4; mTOR, mammalian target of rapamycin; PAR ...

Single-cell analysis revealed the molecular triggers that drive stem cells to become cancerous, which may help inform ...

Brief high-intensity workouts can transform the body faster than traditional long gym sessions by unlocking unique biological ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

The Type C meeting followed a productive End of Phase 2 meeting with FDA and the publication of Phase 2 data of eRapa in FAP at six months at Digestive Disease Week in May 2024 and 12 months data at ...