They coined the term "receptor-mediated endocytosis" to describe the entry of LDL into the cells (Goldstein & Brown 2009). In another series of experiments, Brown and Goldstein used electron ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

it sometimes requires an additional factor such as a protein that is a receptor for a specific chemical serving as a "named ticket to entry" into the cell. One can call its endocytosis that is a ...

After internalization by receptor-mediated endocytosis, the cleaved diphtheria toxin kills the cell by interfering with cellular protein synthesis via ADP ribosylation of elongation factor-2.

Reduced receptor-mediated LDL endocytosis causing raised blood LDL cholesterol (LDL-C) is the main defect, but other abnormalities due to lack of LDL receptors include altered hepatic cholesterol ...