However, cell crowding did not affect the UV-induced DNA damage in either cell type. In this study, we investigated the effects of cell density on the mechanical environment of the cell nucleus and ...

Using advanced imaging techniques and precise microfluidics control to stretch out curly DNA into a straight line, new research demonstrates techniques for stretching and immobilizing DNA with minimum ...

DNA has to be carefully packaged and organized in cells so it will both physically fit into the nucleus, but will also remain accessible to the cell's ... | Genetics And Genomics ...

Dyne Therapeutics is a clinical stage biotech concern with just over $700 million of cash on its balance sheet. Learn more ...

Mysterious Blobs Found inside Cells Are Rewriting the Story of How Life Works Tiny specks called biomolecular condensates are ...

New research reveals that sunburn may be caused by RNA damage, not DNA, challenging long-held beliefs about UV exposure ...

A new study from the Kowalinski group at EMBL Grenoble characterized the structure of an important trypanosomal protein ...

Researchers have previously tried sticking down one end of a DNA molecule to stretch it out, but found that the thermal fluctuations could still cause movement and blurring. "Stretching DNA refers ...

The plasmid DNA vaccine (above) carries the genetic code for a piece of pathogen or tumor antigen. The plasmid vector is taken up into cells and transcribed in the nucleus (1). The single stranded ...

Targeting of scaffolding proteins to specific sites within the nucleus supports their involvement ... combinatorial control of gene expression, DNA replication and repair. Nuclear organization ...

The nucleolus may hold the key. The nucleus holds the cell’s chromosomes and the nucleolus where the ribosomal DNA (rDNA) is housed. The nucleolus isolates the rDNA which encodes the RNA portions of ...