The true incidence of thrombosis among people who received targeted therapy for breast cancer is significantly higher than ...

Rapamycin is used to prevent graft rejection in transplant recipients based on its ability to suppress T-cell proliferation. The drug blocks the activity of a protein known as mammalian target of ...

A deeper understanding of GAC might identify a subset that can benefit from mTOR inhibition. Results More than 30% of GAC cases had alterations (mutations or deletions) of ARID1A and ARID1A expression ...

Biodexa Strengthens Management TeamAppointment of Dr Gary A. Shangold as Chief Medical OfficerBiodexa Pharmaceuticals PLC ...

Emerging evidence suggests a role for PI3K/mTOR signalling in the pathology of organ fibrosis. The aim of this study was to delineate PI3K/mTOR signalling in response to TGF-β 1 stimulation of primary ...

Ghassan K. Abou-Alfa, MD, discusses neratinib and its use as a monotherapy and in combination with immune checkpoint inhibitors and/or mTOR inhibitors in the SUMMIT trial. Ghassan K. Abou-Alfa, MD, a ...

The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to ...

Biodexa Strengthens Management Team Appointment of Dr Gary A. Shangold as Chief Medical Officer Biodexa Pharmaceuticals PLC ("Biodexa" or "the Company"), (Nasdaq: BDRX), a clinical ...