Scientists reveal how filopodia help cancer spread. The breakthrough could improve treatments that stop cancer cells from invading tissues.

Some of the body's cells stay put for life, while others are free to roam. To move, these migratory cells rely on ...

Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.

The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.jpcb.4c07282. Simulation movie of FUS droplet wetting an actin filament ...

Department of Chemical Engineering, University of Virginia, Charlottesville, Virginia 22903, United States Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia 22903 ...

This study presents a valuable finding regarding the role of Arp2/3 and the actin nucleators N-WASP and WAVE complexes in myoblast fusion ... 2019), it is conceivable that macrophages may use these ...

In response, CaMKIIβ dissociates from its bound actin filaments, forming punctate condensates, and becomes the site for FIP200 puncta formation. Importantly, the study demonstrates that CaMKIIβ ...

ASPP1-R: 5′-CTTGTCCTCTCATTGCACGAATT-3′. β-actin-F: 5′-CAGATGTGGATCAGCAAGCAGGA-3′. β-actin-R: 5′-CGCAACTAAGTCATAGTCCGCCTA-3′. After two washes with PBS, total protein was extracted using RIPA buffer, ...