Nagayama, K. and Hirooka, Y. (2025) Changes in the Mechanical Environment of the Nucleus with Cell Crowding and Its Effects on DNA Damage Resistance. Journal of Biosciences and Medicines, 13, 230-242.
This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...
Brian's research focuses intersections between circadian rhythm and cancer. He utilizes cell line and mouse models of MYC-driven lung cancer to focus on how amplified MYC and metabolic stress disrupt ...
An AI foundation model capable of predicting gene activity across many different human cell types may expedite research for genetic disorders, cancer, and complex diseases.
Researchers have identified a unique stem cell in the young brain capable of maturing into multiple cell types, potentially explaining the origins of autism and glioblastoma.