Diabetic nephropathy remains a major complication ... It examines the impact of mTOR on podocytes, glomerular mesangial cells, renal tubular epithelial cells, and glomerular endothelial cells ...

A newly published study in Genes & Diseases highlights the crucial role of the mammalian target of rapamycin (mTOR) pathway in the progression of diabetic nephropathy (DN) and explores its potential ...

Intravenous single-dose studies in normal subjects demonstrate that metformin is excreted unchanged in the urine by renal tubular secretion. The addition of cimetidine 400 mg to metformin 250 mg ...

Polycystic kidney disease (PKD), a family of genetic disorders that causes clusters of cysts to form on the kidney, is among the most common genetic disorders, affecting some 500,000 people in the ...