He lives for belly rubs, soft toys, and quality time with his humans. Ace doesn’t want to share his family with other pets, but his giant heart and playful personality will be more than enough to keep ...

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish. They discovered that the protein Hmga1 plays a key role in ...

In mice, this protein was able to restore the heart by activating dormant repair genes without causing side effects, such as heart enlargement. This study marks an important step toward ...

They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing ...

Artistic representation of heart regeneration: Hmga1 in green symbolically flows from the border zone of a zebrafish heart (top right) to the injured border zone of a mouse heart (left). Red ...

They discovered that the protein Hmga1 plays a key role in heart regeneration in zebrafish. In mice, this protein was able to restore the heart by activating dormant repair genes without causing ...

Recommendations for the authors In this study, Liu, Jiang, Diao et.al. investigated the role of GSDMD in psoriasis-like skin inflammation in mice. The authors have used full-body GSDMD knock-out mice ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

These results suggested that the cardiac function deteriorate with the increase in the accumulation of drugs in mice. HE staining was performed to further clarify the histological changes in the heart ...

Hematoxylin and eosin (HE) staining and Oil Red O staining reagents were acquired from Wuhan Seville Biology Co., LT (Wuhan, Hubei, China). Thirty-two male BALb/c mice (weighing 18–22 g and aged 6–8 ...