In that respect it follows a similar model to Merck's takeover of AmpTec, another CDMO that uses a PCR platform to make mRNA drugs, for an undisclosed sum last year. Outsourcing services are on of ...

The 25,000-subject study is testing a nucleoside-modified mRNA (modRNA), quadrivalent vaccine that is targeted against four strains of the flu virus that the World Health Organization (WHO ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

A population-based congenital cytomegalovirus screening program in Ontario successfully screened 551,034 newborns; of those ...

Australian researchers have made a breakthrough in improving the cure rate for the most common form of breast cancer. An ...

METHODS Intestinal biopsy specimens, isolated lamina propria cells (LPMC), and peripheral blood mononuclear cells (PBMC) were cultured with or without butyrate for assessment of secretion of tumour ...

Wearing a medical-grade mask or respirator can decrease the risk of infection. Good hand hygiene and proper sneezing and cough etiquette can also decrease the risk of transmission.

AArly DETECT 2 feasibility study designed to validate earlier results on advanced adenomas over a large population of average risk ...

IL-17 mRNA expression was analysed by reverse transcriptase-polymerase chain reaction. Conclusions: IL-17 expression in the mucosa and serum was increased in IBD patients. It is likely that IL-17 ...

RNA is generally single-stranded, as DNA is transcribed by RNA polymerases into mRNA (messenger RNA), which is read by ribosomes to generate protein (translation). Biologically active RNAs ...

表观遗传修饰在多种生物和病理过程中起着关键作用，其中5-甲基胞嘧啶（5mC）被认为是肿瘤发生和进展的早期分子事件，并已成为一个非常有前景的生物标志物。近年来，5-羟甲基胞嘧啶（5hmC）作为5mC的氧化产物，在正常哺乳动物生长和发育中也扮演着重要角色，并与癌症和神经疾病等疾病相关，显示出作为癌症诊断理想生物标志物的巨大潜力。然而，由于5hmC水平比5mC低约14倍，且其结构与C和5mC相似，使得5 ...

The VDH and Scott are advocating for people to get their vaccinations before winter. Scott said he has received his COVID ...