The isothermal nucleic acid amplification technology market has evolved significantly due to the growing need for decentralized and point-of-care diagnostics. The increasing emphasis on rapid ...

such as polymerase chain reaction (PCR), and thermal-independent amplification, rolling circle amplification (RCA), recombinase polymerase amplification (RPA), or loop-mediated isothermal ...

The detection platform, which was designed by employing MCDA for rapid amplification of the speB gene at 63 °C for 40 min and the CRISPR-Cas12a technique for detecting the target amplicons and results ...

5,15 Additionally, both SHERLOCK and DETECTR often incorporate isothermal amplification techniques, such as recombinase polymerase amplification (RPA), to enhance the sensitivity of detection ...

where the polymerase adds nucleotides to the growing DNA strand. Mokry set up his experiment, running the amplification with their chimeric DNA polymerase. Then, he handed the samples to Nick Courtney ...

View Full Profile. Learn about our Editorial Policies. Polymerase chain reaction (PCR) is a fundamental molecular biology tool that scientists use to amplify and analyze genetic material, such as DNA ...

Errors during transcription may play an important role in determining cellular phenotypes: the RNA polymerase error rate is >4 orders of magnitude higher than that of ...

The DNA Polymerase α (Pol α)/primase complex initiates DNA synthesis in eukaryotic replication. In the complex, Pol α and primase cooperate in the production of RNA-DNA oligonucleotides that prime ...