The team focused its attention on the striatum, a region within the brain's basal ganglia, where neurons use dopamine to influence neural circuits involved in a variety of processes, including ...
A large number of computational models of information processing in the basal ganglia have been developed in recent years. Prominent in these are actor-critic models of basal ganglia functioning which ...
The basal ganglia, a complex network of nuclei deeply situated in the brain, plays a pivotal role in diverse cognitive and motor functions. Consisting of key structures such as the striatum, globus ...
While the above models seek the consequences of dopamine depletion on the dynamics of the striatum and wider basal ganglia network, others have pursued the equally profound question of how the loss of ...
In contrast to most other brain regions, in the striatum the output neurons (the medium-sized spiny neurons, MSNs) are GABAergic and act by inhibiting their targets. The standard model of the basal ...
In particular, this model comprises 10 neural populations that correspond to the four major nuclei of the biological basal ganglia and form their canonical circuit. These include the striatum ...
Dopaminergic neurons in the basal ganglia normally fire in a random but continuous manner, so that striatal dopamine concentrations are maintained at a relatively constant level. In the dopamine ...
The model also made specific, empirically falsifiable predictions that can be used to explore the utility of these putative mechanisms of information processing in the frontal cortex and basal ganglia ...
This dispersion was not limited to the basal ganglia; grafted MGE cells also ... Neurobasal medium and microinjected (0.1 μl) into striatum of adult mouse. Brains were processed 20 and 48 hours ...
Initial CT of the head revealed hypodensities within the right basal ganglia and medial temporal lobe. MRI T2 FLAIR sequence showed unilateral signal abnormalities in the right temporal lobe, right ...
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