APOE Gene Test: What It Is, How It Works & Results - Cleveland Clinic
2024年8月21日 · An APOE gene test is a type of genetic test that identifies which variant of the apolipoprotein E (APOE) genotype you have. Having certain APOE genotypes may mean you …
Apolipoprotein E: structure and function in lipid metabolism ... - PubMed
Apolipoprotein (apo) E is a multifunctional protein with central roles in lipid metabolism, neurobiology, and neurodegenerative diseases. It has three major isoforms (apoE2, apoE3, …
APOE gene - MedlinePlus
The APOE gene provides instructions for making a protein called apolipoprotein E. Learn about this gene and related health conditions.
Apolipoprotein E and Alzheimer disease: risk, mechanisms, and …
Apolipoprotein E (ApoE) is a major cholesterol carrier that supports lipid transport and injury repair in the brain. APOE polymorphic alleles are the main genetic determinants of Alzheimer …
Apolipoprotein E - A Multifunctional Protein with Implications in ...
Apolipoprotein E (apoE), a 34 kDa glycoprotein, mediates hepatic and extrahepatic uptake of plasma lipoproteins and cholesterol efflux from lipid-laden macrophages. In humans, three …
Apolipoprotein E - an overview | ScienceDirect Topics
Apolipoprotein E (apoE) is a major apolipoprotein involved in lipoprotein metabolism. It is a polymorphic protein and different isoforms are associated with variations in lipid and …
Apolipoprotein E: from lipid transport to neurobiology - PMC
Apolipoprotein E (apoE) is a potent modulator of plasma lipoprotein and cholesterol levels whose mode of action is mediated by interaction with members of the low-density lipoprotein (LDL) …
Apolipoprotein E: far more than a lipid transport protein
First recognized as a major determinant in lipoprotein metabolism and cardiovascular disease, apolipoprotein (apo) E has emerged as an important molecule in several biological processes …
Apolipoprotein E: from cardiovascular disease to neurodegenerative ...
Apolipoprotein (apo) E was initially described as a lipid transport protein and major ligand for low density lipoprotein (LDL) receptors with a role in cholesterol metabolism and cardiovascular …
Apolipoprotein E: Structural Insights and Links to Alzheimer …
2020年11月10日 · Apolipoprotein E (ApoE) is of great interest due to its role as a cholesterol/lipid transporter in the central nervous system (CNS) and as the most influential genetic risk factor …
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