Contact inhibition controls cell survival and proliferation ... - Nature
2018年7月27日 · Contact inhibition enables noncancerous cells to cease proliferation and growth when they contact each other. This characteristic is lost when cells undergo malignant...
Contact inhibition - Wikipedia
Furthermore, recent studies have further revealed some mechanisms of contact inhibition of proliferation and its potential implications in cancer therapy. Furthermore, it has been shown …
The Development and Causes of Cancer - The Cell - NCBI …
Contact inhibition. Light micrographs (left) and scanning electron micrographs (right) of normal fibroblasts and tumor cells. The migration of normal fibroblasts is inhibited by cell contact, so …
A revisited concept: Contact inhibition of growth. From cell …
2017年10月1日 · Contact inhibition is one of the key processes deregulated in transformed cells during carcinogenesis. The majority of cancer cells are refractory to the confluence-induced …
E-cadherin in Contact Inhibition and Cancer - PMC - PubMed …
Loss of E-cadherin expression results in loss of contact inhibition and is associated with increased cell motility and advanced stages of cancer. In this review we discuss the role of E-cadherin …
Close Encounters of the Cell Kind: The Impact of Contact Inhibition on ...
An outstanding and important question concerns contact inhibition of proliferation (CIP), the observation that proliferation ceases when cells are spatially confined by their neighbours. CIP …
Loss of E-cadherin expression results in loss of contact inhibition and is associated with increased cell motility and advanced stages of cancer. In this review we discuss the role of...
E-cadherin in contact inhibition and cancer | Oncogene - Nature
2018年5月21日 · Loss of E-cadherin expression results in loss of contact inhibition and is associated with increased cell motility and advanced stages of cancer. In this review we …
E-cadherin in contact inhibition and cancer - PubMed
Loss of E-cadherin expression results in loss of contact inhibition and is associated with increased cell motility and advanced stages of cancer. In this review we discuss the role of E-cadherin …
Contact inhibition and high cell density deactivate the ... - PNAS
2014年6月2日 · In cancer cells, lacking CI, mTOR was still inhibited in high cell density by an alternative mechanism. Our work explains why CI is reversible and how cells can avoid …
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