Nucleolar histone deacetylases HDT1, HDT2, and HDT3 …
2022年1月1日 · Here, we report the critical role of three Arabidopsis nucleolar proteins HDT1, HDT2, and HDT3 in fertility and transcription of rDNAs and rRNA processing-related genes through histone acetylation. This study highlights the important roles of transcriptional repression of ribosome biogenesis-related genes for plant reproductive development.
Plant-specific HDT family histone deacetylases are nucleoplasmins
2022年9月7日 · Here, we solved the crystal structure of the N-terminal domain (NTD) of all four HDTs (HDT1, HDT2, HDT3, and HDT4) from Arabidopsis (Arabidopsis thaliana). The NTDs form a nucleoplasmin fold, exist as pentamers in solution, and are resistant to protease treatment, high temperature, salt, and urea conditions.
Histone Deacetylase HDT1 is Involved in Stem Vascular
2019年7月13日 · Histone acetylation and deacetylation play essential roles in eukaryotic gene regulation. HD2 (HD-tuins) proteins were previously identified as plant-specific histone deacetylases. In this study, we investigated the function of the HDT1 gene in the formation of stem vascular tissue in Arabidopsis thaliana.
Plant-Specific Histone Deacetylases HDT1/2 Regulate
2017年9月8日 · Here, we show that two Arabidopsis thaliana paralogs encoding plant-specific histone deacetylases, HDT1 and HDT2, regulate a second switch from transit-amplifying cells to expanding cells. Knockdown of HDT1/2 (hdt1,2i) results in an earlier switch and causes a reduced RM cell number.
(PDF) Histone Deacetylase HDT1 is Involved in Stem
2019年7月13日 · Histone acetylation and deacetylation play essential roles in eukaryotic gene regulation. HD2 (HD-tuins) proteins were previously identified as plant-specific histone deacetylases. In this study,...
HD2 (HD-tuins) proteins were previously identified as plant-specific histone deacetylases. In this study, we investigated the function of the HDT1 gene in the formation of stem vascular tissue in...
Histone Deacetylase Genes in Arabidopsis Development
2008年8月1日 · HDAC6, an RPD3/HDA1-type deacetylase in Arabidopsis, represses the defense-responsive genes PR1, PR2 and WRKY38 by removing H3Ac levels, subsequently compromising plant defense against...
Histone Deacetylase HDT1 is Involved in Stem Vascular …
Results suggested that HDT1 is involved in development of the vascular tissue of the stem by affecting cell proliferation and differentiation in Arabidopsis thaliana. Histone acetylation and deacetylation play essential roles in eukaryotic gene regulation.
Histone Deacetylase Genes in Arabidopsis Development
2008年7月15日 · This review is focused on the family of histone deacetylases (HDACs) that remove the acetyl group from core histone tails, resulting in a “closed” chromatin and transcriptional repression. In Arabidopsis, 18 HDAC genes are divided into three different types – RPD3-like, HD-tuin and sirtuin – with two or more members in each type. The ...
Histone deacetylation-mediated cellular dedifferentiation in Arabidopsis
2016年2月1日 · The Arabidopsis genome encodes 18HDAC genes of three types: Reduced Potassium Deficiency 3 (RPD3), HD-tuin, and sirtuin (Hollender and Liu, 2008). Since HDAC activities were shown to be involved in leaf-to-callus transition (Fig. 1), we aimed to determine which HDAC members are implicated in cellular dedifferentiation.